Simparica Trio for Dogs 44.1-88 lbs., 6 Month Supply Supplement Facts

Name: Simparica Trio for Dogs 44.1-88 lbs., 6 Month Supply
Brand: Simparica Trio
Rating: 3.82 (365 reviews)

Simparica Trio for Dogs 44.1-88 lbs., 6 Month Supply is a dog heart and liver supplement in tablet form.

Supplement facts

Sarolaner, Moxidectin, Pyrantel pamoate

Values above are transcribed from the product label exactly as printed. Supplements are not reviewed or approved by the FDA to treat, cure, or prevent disease, and independent testing shows label accuracy varies between brands. Always check with your veterinarian before starting a supplement.

Directions

Simparica is given orally once a month at the recommended minimum dosage according to your dog's weight. Simparica can be offered by hand, in the food, or administered like other oral tablet medications. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused.

Cautions

Not for use in humans. Keep this and all drugs out of reach of children. MORE INFORMATION Product details Simparica Trio is a pork liver-flavored chewable tablet administered once per month to protect your dog from heartworm disease, fleas, ticks, roundworms, and hookworms. Please note: Due to a manufacturer redesign, the same trusted formulation is receiving new, easier-to-read packaging. Your medication may arrive with this updated packaging, depending on manufacturer availability. Simparica Trio is the first FDA-approved monthly chewable that protects your dog against heartworm disease, ticks, fleas, roundworms, and hookworms. Approved for puppies as young as eight weeks old and weighing at least 2.8 pounds. Studies to support FDA-approval showed one dose provided 100% protection against heartworm disease. Simparica Trio is the first FDA-approved product of its kind and the only one approved to prevent Lyme infections as a direct result of killing deer ticks. It’s proven to kill five types of ticks including the Gulf Coast Tick, Deer Tick, American Dog Tick, Lone Star Tick...

Ingredients

Inactive ingredients

Complete inactive ingredients list not provided by manufacturer. Brand name Simparica Trio Drug class Isoxazoline ectoparasiticide, Macrocyclic lactone antiparasitic, Tetrahydropyrimidine anthelmintic Product flavoring Simparica Trio is a pork liver flavored chewable tablet. _\*Contains pork, soy, lactose, corn, wheat_ Manufacturer Zoetis Product strength & size | Weight Range | Sarolaner (per tablet) | Moxidectin (per tablet) | Pyrantel (per tablet) | | --- | --- | --- | --- | | 2.8 to 5.5 lbs | 3 mg | 0.06 mg | 12.5 mg | | 5.6 to 11 lbs | 6 mg | 0.12 mg | 25 mg | | 11.1 to 22 lbs | 12 mg | 0.24 mg | 50 mg | | 22.1 to 44 lbs | 24 mg | 0.48 mg | 100 mg | | 44.1 to 88 lbs | 48 mg | 0.96 mg | 200 mg | | 88.1 to 132 lbs | 72 mg | 1.44 mg | 300 mg | \*For dogs over 132 lbs, administer the appropriate combination of tablets to cover your pet’s body weight. -- Usage _\*For complete product information, please review the full prescribing information in the manufacturer package insert._ Simparica Trio should be given orally at monthly intervals year-round...

Full ingredient list

Sarolaner, Moxidectin, Pyrantel pamoate

Frequently asked questions

What is Simparica Trio for Dogs 44.1-88 lbs., 6 Month Supply for?

Simparica Trio for Dogs 44.1-88 lbs., 6 Month Supply is formulated as a heart and liver supplement for dogs.

About this data

Data sources: Petco.

Data was compiled manually and may be out of date.

Data last updated July 11, 2026.

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About this data

We gather factual supplement details from public manufacturer and retailer listings and product labels. Values are shown exactly as printed on each label. Supplements are not reviewed or approved by the FDA to treat, cure, or prevent disease, and label accuracy varies by brand. Nothing here is veterinary advice, and no product listed here is endorsed. Always check with your veterinarian before starting a supplement. Product names and trademarks belong to their respective owners.

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